Case Studies/A mathematical way to think about biology

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To fully realize the potential benefit of collaboration between the biological and physical sciences, the initiatives of the Office of Physical Sciences Oncology (physics.cancer.gov) must accomplish more than simply continuing the development of measurement technologies. Moore et al. have commented that previous "contributions [i.e. x-rays, PET, and MRI] leverage the technology development aspect from the physical sciences . . . but not other important aspects like methodology, practices and thought processes. What is different about the NCI’s PS-OC Program is the conviction that unique physical sciences and engineering approaches and principles can be integrated . . . in cancer research to yield a more fundamental understanding of the disease."

One of these physical sciences "thought processes" is quantitative reasoning. Resources for developing this skill currently include introductory courses in quantitative biology. For example, Los Alamos National Laboratories hosts the invaluable q-Bio summer school (q-bio.org). However, mathematical prerequisites for these courses pose a challenge for investigators trained in many life sciences fields. A mathematical way to think about biology was developed to help address this challenge. This website is a collection of video tutorials to help biologists, clinicians, and patient advocates prepare for courses in quantitative biology. The purpose of these videos is to provide familiarity with introductory topics often presented in quantitative biology courses and confidence to actively learn the more sophisticated concepts that are developed from these foundations.

To ensure broadest delivery of this resource, the slides and videos are made available under a CC BY-SA license.

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